錳元素（賴氨酸錳Manganese Lysinate）在動物代謝中的關(guān)鍵作用

錳（賴氨酸錳Manganese Lysinate）作為動物體內(nèi)不可或缺的重要元素，深度參與葡萄糖、蛋白質(zhì)、尿素等物質(zhì)的循環(huán)代謝過程。其主要作用機制是調(diào)節(jié)代謝過程中酶的活力，在飼料中合理添加錳（賴氨酸錳Manganese Lysinate），對維持動物體的正常代謝意義重大。相關(guān)研究表明，在日糧中補充有機錳和無機錳，能有效增加羊羔肝臟中錳的沉積量，同時提升錳超氧化物歧化酶（Mn-SOD）和精氨酸酶的活性。精氨酸酶作為錳的依賴性酶，在肝臟尿素循環(huán)代謝的最后環(huán)節(jié)發(fā)揮著關(guān)鍵作用。丙酮酸羧化酶是糖異生過程中的關(guān)鍵酶，能將丙酮酸羧化為草酰乙酸，它是三羧酸循環(huán)和糖異生的連接轉(zhuǎn)換點，且其激活高度依賴錳，這使得錳直接參與糖異生，并間接參與三羧酸循環(huán)。此外，崔德汶的研究顯示，添加 485mg/kg 的氨基酸錳可提高綿羊瘤胃中丙酸生成量，為肝臟糖異生提供有力支持。孫昱等的研究則發(fā)現(xiàn)，隨著日糧中錳含量增加，血液中谷丙轉(zhuǎn)氨酶含量顯著升高，飼喂錳含量為 60mg/kg 的飼料，對遼寧絨山羊蛋白質(zhì)代謝提升效果顯著。

錳元素（賴氨酸錳Manganese Lysinate）在動物代謝中的關(guān)鍵作用

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The key role of the manganese element (lysine manganese lysinate) in animal metabolism

As an indispensable and important element in animals, manganese (manganese lysine) is deeply involved in the circulation and metabolism of glucose, protein, urea and other substances. Its main mechanism of action is to regulate the activity of enzymes in the metabolic process, and the reasonable addition of manganese (Manganese lysine) to the feed is of great significance to maintain the normal metabolism of animals. Relevant studies have shown that supplementation of organic manganese and inorganic manganese in the diet can effectively increase the amount of manganese deposition in the liver of lambs, and increase the activities of manganese superoxide dismutase (Mn-SOD) and arginase. Arginase, as a manganese-dependent enzyme, plays a key role in the final link of hepatic urea cycle metabolism. Pyruvate carboxylase is a key enzyme in the process of gluconeogenesis, which can carboxylize pyruvate into oxaloacetate, which is the junction transition point between the tricarboxylic acid cycle and gluconeogenesis, and its activation is highly dependent on manganese, which makes manganese directly involved in gluconeogenesis and indirectly involved in the tricarboxylic acid cycle. In addition, Cui Dewen's study showed that the addition of 485mg/kg of manganese amino acid can increase the production of propionic acid in the rumen of sheep, providing strong support for hepatic gluconeogenesis. Sun Yu et al.'s study found that with the increase of manganese content in the diet, the content of alanine aminotransferase in the blood increased significantly, and feeding a feed with a manganese content of 60mg/kg had a significant effect on the protein metabolism of Liaoning cashmere goats.

The key role of the manganese element (lysine manganese lysinate) in animal metabolism

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