氨基酸鈣（Calcium Amino Acid Chelate）的螯合機制：分子特性與穩定化策略的協同作用

氨基酸鈣（Calcium Amino Acid Chelate）作為金屬螯合物，其制備本質是通過氨基酸分子中氨基（-NH2）和羧基（-COOH）的共價配位，與鈣離子（Ca2+）形成空間穩定的五元或六元螯合環結構。這一過程中，氨基酸的分子量、側鏈基團類型及供電子能力直接影響螯合物的穩定性：小分子氨基酸（如甘氨酸）因分子鏈短、空間位阻小，更易通過單齒或雙齒配位與鈣離子結合；而帶羥基（如絲氨酸）、硫醇基（如半胱氨酸）等功能基團的氨基酸，可形成氫鍵或氧化還原敏感的多維配位網絡，顯著提高螯合物的結構穩定性。實驗表明，不同氨基酸的螯合常數（log K）差異可達3-4個數量級，例如谷氨酸鈣的log K值（8.2）顯著高于丙氨酸鈣（3.5）。因此，螯合工藝需針對性調控：對于強配位型氨基酸（如天冬氨酸），通過pH調控（6.0-7.5）強化羧酸根的負電荷；而對弱配位型氨基酸（如纈氨酸），則引入紫外輻照或微波輔助技術，激活α-氨基的孤對電子，最終實現螯合物穩定性的定向優化。

氨基酸鈣（Calcium Amino Acid Chelate）的螯合機制：分子特性與穩定化策略的協同作用

公司官網：www.wilincare.net歡迎選購！

抗壞血酸鎂Magnesium Ascorbate 、抗壞血酸鋅Magnesium Ascorbate、牛磺酸鎂Magnesium Taurate、氨基酸螯合鋅Zinc Amino Acids Chelate 、氨基酸螯合鎂Magnesium Amino Acids Chelate、乳清酸鎂Magnesium Orotate、乳清酸鈣Calcium Orotate、琥珀酸鈣Calcium Succinate、琥珀酸鎂 Magnesium Succinate 、抗壞血酸鋰 Lithium Ascorbate.

The chelation mechanism of calcium amino acid (Calcium Amino Acid Chelate): Synergistic effects of molecular properties and stabilization strategies

Calcium Amino Acid Chelate is a metal chelate. Its preparation essence is to form a sterically stable five-membered or six-membered chelating ring structure with calcium ions (Ca2+) through the covalent coordination of amino (-NH2) and carboxyl (-COOH) in amino acid molecules. During this process, the molecular weight, side chain group type and electron donation capacity of the amino acid directly affect the stability of the chelate: small-molecular amino acids (such as glycine) are more likely to bind to calcium ions through single or double teeth coordination due to their short molecular chain and small steric hindrance; while amino acids with functional groups such as hydroxyl groups (such as serine) and thiol groups (such as cysteine) can form a multi-dimensional coordination network that is sensitive to hydrogen bonds or redox, significantly improving the structural stability of the chelate. Experiments show that the chelation constant (log K) of different amino acids can vary by 3-4 orders of magnitude, for example, the log K value of calcium glutamate (8.2) is significantly higher than that of calcium alanine (3.5). Therefore, the chelation process needs to be targeted: for strong coordination amino acids (such as aspartic acid), the negative charge of the carboxylate is strengthened through pH regulation (6.0-7.5); for weak coordination amino acids (such as valine), ultraviolet irradiation or microwave assisted technology is introduced to activate the lone pair of α-amino electrons, and ultimately achieve directional optimization of chelate stability.

The chelation mechanism of calcium amino acid (Calcium Amino Acid Chelate): Synergistic effects of molecular properties and stabilization strategies

Company official website: www.wilincare.net Welcome to purchase!

Magnesium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbate, Magnesium Taurate, Zinc Amino Acids Chelate, Magnesium Amino Acids Chelate, Magnesium Orotate, Calcium Orotate, Calcium Succinate, Magnesium Succinate, Lithium Ascorbate.